Fig. 6

LINC00853 significantly accelerated tumor progression of GC cells in vivo. The photos of the tumor xenografts (A) and the tumor volume curve (B-C) and the tumor weight graph (D) of xenograft tumors generated via subcutaneous administration of MGC803 and MKN-78 cells stably transfected with sh-LINC00853 or LINC00853 OE, respectively. E Detection of proliferation in tumor tissues with Ki67 staining assay. Scale bar = 50 μm. F ImageJ software was utilized to quantify the number of Ki67-positive cells in tumor tissue. G The level of LINC00853 was clarified via RT-PCR test. H, I Western blot assay was applied to illustrate the level of PDZK1IP1. *p < 0.05, **p < 0.01