Fig. 6

Correlation analysis between CLSPN expression and five MMR genes and four DNA methyltransferases in pan-cancer. A The heatmap of association between CLSPN expression and five MMR genes (MLH1, MSH2, MSH6, EPCAM, PMS2). B The heatmap of correlation between CLSPN expression and the expression of four methyltransferases (DNMT1, DNMT2, DNMT3A, DNMT3B). C Spearman’s correlation analysis of CLSPN expression with four DNA methyltransferases across 33 cancers. *P < 0.05, **P < 0.01, ***P < 0.001