Fig. 2

BPTF exerts a promotional role in neuroblastoma cell growth. A Representative expression of BPTF after 96 h infection with BPTF knockdown lentiviral, as detected by western blot. B BPTF western blot analysis in SK-N-BE(2) cell [mean, 0.904 vs. 0.302 vs. 0.377]. C-D SK-N-BE(2) cell growth following BPTF depletion (C) and using AU1 (D) shown by RTCA. Error bars represent SD. E–F SK-N-BE(2) cell growth following BPTF depletion [mean, 73.667 vs. 25.000 vs. 35.667, E] and using AU1 [mean, 101.667 vs. 28.333 vs. 10.000 vs. 2.000, F] shown by colony formation assay. Error bars represent SEM. The data are representative of at least three independent experiments. ** P < 0.01, *** P < 0.001, **** P < 0.0001, as assessed by Student’s t-tests