Fig. 5

CSNK1D activated the Wnt/β-catenin signaling of HCC cells. A The volcano figure identifying the DEGs between CSNK1D-high and CSNK1D-low patients in TCGA dataset. B-F Gene sets enrichment analysis (GSEA) of the CSNK1D-mediated pathways in TCGA LIHC cohort. G The EMT markers were detected by Western blotting. H The markers of Wnt/β-catenin signaling were detected by Western blotting. I The activity of Wnt/β-catenin pathway was detected with CSNK1D overexpression and XAV939 treatment, along with CSNK1D knockdown and Wnt3a treatment. J The expression and location of β-catenin was detected by immunofluorescence in HepG2 and MHCC97H cells with CSNK1D overexpression and knockdown, respectively