Fig. 2

Prognostic significance of the circadian genes-based signature. A Receiver operating characteristic (ROC) curves were calculated to evaluate the predictive efficiency of the circadian signature. B The Kaplan–Meier curves of HCC patients at the high-risk score group and low-risk score group in TCGA cohort. C, D Univariate and Multivariate Cox analyses of the clinicopathological factors (including the risk score) and overall survival in TCGA LIHC cohort. E, F The Kaplan–Meier curves for HCC patients at early or advanced stages in TCGA cohort. G, H The Kaplan–Meier curves for HCC patients at early or advanced stages in TCGA cohort