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Fig. 1 | Biological Procedures Online

Fig. 1

From: Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/β-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3

Fig. 1

Genomic Alterations of the Circadian genes in TCGA LIHC Cohort A The heatmap showed the expression profiles of 28 circadian genes in HCC and normal liver tissue from the Cancer Genome Atlas (TCGA) liver hepatocellular carcinoma (LIHC) dataset. B Univariate Cox regression was performed to screen circadian genes with prognostic value. Ten- circadian gene based signature with coefficients (CSNK1D, TIPIN, NPAS2, GSK3B, RORC, CRY2, CSNK1E, PER1, SERPINE1, NR1D1) was calculated by multivariate Cox regression with least absolute shrinkage and selection operator (LASSO). D Expression characteristics and clinicopathological distribution of the signature genes in TCGA LIHC datasets

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