Evaluation of method performance for oxidative stress biomarkers in urine and biological variations in urine of patients with type 2 diabetes mellitus and diabetic nephropathy

Table 3 Biological variation components in patients with T2DM or DN and healthy individuals

	^a CV _TI (%)	^b CV _G (%)	^c II	^d RCV (%)
T2DM patients
CAT	18.09	32.07	0.56	50.10
CuZnSOD	14.45	27.03	0.53	40.02
MDA	31.39	17.28	1.81	86.95
DN patients
CAT	15.14	29.67	0.51	41.93
CuZnSOD	8.61	24.02	0.35	23.84
MDA	25.40	16.25	1.56	70.35
Healthy Individuals
CAT	9.08	23.48	0.38	27.92
CuZnSOD	5.60	31.08	0.18	15.51
MDA	21.00	11.96	1.50	49.86

While the results of CAT and CuZnSOD activities were expressed as U/L, MDA concentration was expressed as nmol/mL.
^aCV_TI, within-subject coefficient of variation; ^bCV_G, between-subject coefficient of variation; ^cII, index of individuality; ^dRCV, reference change value (with 95% confidence).

ISSN: 1480-9222